2. Anti-CCP Antibody

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Anti CCP Antibodies in Tuberculosis.

INTRODUCTION Anti-cyclic citrullinated peptide (anti-CCP) antibodies have been considered very specific for rheumatoid arthritis (RA). Some studies have shown that these antibodies can be positive in infectious diseases like TB, HIV, etc. METHODS Fifty patients of tuberculosis both pulmonary and extra-pulmonary were enrolled in the study from inpatient and outpatient departments from May 2012...

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Anti-CCP Antibody Levels Are Not Associated with MS: Results from a Case-Control Study

Citrullinated proteins have been suggested to play a critical role in the pathogenesis of multiple sclerosis (MS). Anticyclic citrullinated peptide (anti-CCP) antibody is used in the early diagnosis of rheumatoid arthritis (RA). The objective of this study was to investigate the presence of anti-CCP antibody in patients with MS compared to RA patients and healthy controls. Fifty patients with M...

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Q: Should I order an anti-CCP antibody test to diagnose rheumatoid arthritis?

Yes. Testing for anti-cyclic citrullinated peptide (anti-CCP) antibody can help diagnose rheumatoid arthritis (RA) because it is a highly specific test. For many years, the diagnosis of RA has been based on the presentation of symmetrical smalland large-joint polyarthritis that spares the lower spine, further supported by the presence of characteristic joint damage on radiography and an elevate...

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Anti-CCP: History and its Usefulness

Antibodies directed to cyclic citrullinated peptides (anti-CCP) are highly specific for rheumatoid arthritis (RA) and can easily be detected in sera by using commercially available immunoassays. The second version of the anti-CCP test (anti-CCP2) demonstrated high specificity (89-98%) and good sensitivity (41-88%) for RA. Commercially available ELISA methods from three different companies are o...

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Anti-CCP antibody testing as a diagnostic and prognostic tool in rheumatoid arthritis.

Rheumatoid arthritis is both common and chronic, with significant consequences for multiple organ systems. Better understanding of its pathophysiology has led to the development of targeted therapies that have dramatically improved outcomes. The key to therapeutic success lies in identifying individuals who will have severe destructive disease as early as possible, so that effective treatment c...

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ژورنال

عنوان ژورنال: Nihon Naika Gakkai Zasshi

سال: 2007

ISSN: 0021-5384,1883-2083

DOI: 10.2169/naika.96.2132